Argonne National Laboratory Biosciences Division
> Publications		 DOE Logo
Argonne Home > BIO home > Frank Collart

Frank Collart

Publications by Author,
Select Publication Author 		 
   
     

PUBLICATIONS

Submitted

  1. Crystal Structure of YkuI in Complex with Second Messenger c-di-GMP Suggests Catalytic Mechanism of Phosphodiester Bond Cleavage by Eal Domains. Minasov,G. Padavattan, S., Shuvalova, L.,  Brunzelle, J.S. Miller,  D.J., Baslé, A., F Collart, F. R, Schirmer, T., and Anderson, W.F.  J. Biol. Chem. Submitted for Publication.
  2. Jovanovic, I., Magnuson, J. K., Collart, F. R., Robbertse, B., Schoch, C. L., Adney, W. S., Himmel, M.,  and Baker, S. E. Overview of the Diversity of Fungal Glycoside Hydrolases: Outlook for new Discoveries. Cellulose Submitted for Publication.

 

Published/Accepted for Publication

  1. "Pinchuk,  G.E., Rodionov, D. A., Yang, C., Li, X., Osterman, A. L., Dervyn, E., Geydebrekht, O.V., Reed, S. B., Romine, M. F., Collart, F.R., Scott, J. H., Fredrickson, J. K., and Beliaev, A. S. Genomic Reconstruction of Shewanella Oneidensis MR-1 Metabolism Reveals a Novel Machinery for Lactate Utilization. Proc. Natl. Acad. Sci. U S A., Accepted for Publication.
  2. Osipiuk J, Zhou M, Moy S, Collart F, Joachimiak A. X-Ray crystal structure of GarR-tartronate semialdehyde reductase from Salmonella typhimurium. J Struct Funct Genomics. 2009 Jan 28. [Epub ahead of print].
  3. Abdullah, J., Joachimiak, A, and Collart, F. R. “System 48” High Throughput Cloning and Protein Expression Analysis. Methods Mol Biol. 498:117-27, 2009
  4. Giuliani, S. E., Frank, A. M., and Collart, F. R. Functional Assignment of Solute-Binding Proteins of ABC Transporters Using a Fluorescence-Based Thermal Shift Assay. Biochemistry 47(52) 13974-84, 2008.
  5. Yuri Y. Londer, Sarah E. Giuliani, Terese Peppler, Frank R. Collart. Addressing Shewanella oneidensis “cytochromome”: the first step towards high-throughput expression of cytochromes c. Protein Expression and Purification 62(1) 128-37, 2008
  6. Younggyu Kim, Sam On Ho, Natalie R. Gassman, You Korlann, Elizabeth V. Landorf, Frank Collart, and Shimon Weiss.  Efficient site-specific labeling of proteins via cysteines. Bioconjugate Chemistry 3 786-91, 2008.
  7. Structural Genomics Consortium; China Structural Genomics Consortium; Northeast Structural Genomics Consortium, Gräslund S, Nordlund P, Weigelt J, Bray J, Gileadi O, Knapp S, Oppermann U, Arrowsmith C, Hui R, Ming J, dhe-Paganon S, Park HW, Savchenko A, Yee A, Edwards A, Vincentelli R, Cambillau C, Kim R, Kim SH, Rao Z, Shi Y, Terwilliger TC, Kim CY, Hung LW, Waldo GS, Peleg Y, Albeck S, Unger T, Dym O, Prilusky J, Sussman JL, Stevens RC, Lesley SA, Wilson IA, Joachimiak A, Collart F, Dementieva I, Donnelly MI, Eschenfeldt WH, Kim Y, Stols L, Wu R, Zhou M, Burley SK, Emtage JS, Sauder JM, Thompson D, Bain K, Luz J, Gheyi T, Zhang F, Atwell S, Almo SC, Bonanno JB, Fiser A, Swaminathan S, Studier FW, Chance MR, Sali A, Acton TB, Xiao R, Zhao L, Ma LC, Hunt JF, Tong L, Cunningham K, Inouye M, Anderson S, Janjua H, Shastry R, Ho CK, Wang D, Wang H, Jiang M, Montelione GT, Stuart DI, Owens RJ, Daenke S, Schütz A, Heinemann U, Yokoyama S, Büssow K, Gunsalus KC.  Protein production and purification.  . Nat Methods. 5(2):135-46, 2008.
  8. Nocek B, Mulligan, R., Bargassa, M., Collart, F., and Joachimiak A.  Crystal Structure of Aminopeptidase N from Human Pathogen Neisseria meningitides. Proteins. 2008, 70:273-9.
  9. Vorontsov II, Minasov G, Brunzelle JS, Shuvalova L, Kiryukhina O, Collart F.R., Anderson WF. Crystal structure of an apo form of Shigella flexneri ArsH protein with an NADPH-dependent FMN reductase activity. Protein Sci. 11:2483-2490, 2007.
  10. Kolker, E., Hogan, J.M., Higdon, R., Kolker, N., Landorf, E., Yakunin, A.F., Collart, F.R., van Belle, G.  Development of BIATECH-54 standard mixtures for assessment of protein identification and relative expression.  Proteomics. 20:3693-8, 2007.
  11. Michael H. Godsey, George Minasov, Ludmilla Shuvalova, Joseph S. Brunzelle, Ivan I. Vorontsov, Frank R. Collart, Wayne F. Anderson. The 2.2 Å Resolution Crystal Structure of Bacillus cereus Nif3-family protein YqfO, reveals a conserved dimetal-binding motif and a regulatory domain.  Protein Sci. 7:1285-93, 2007.
  12. Stols, L.;Zhou, M.; Eschenfeldt, W.H.; Sanville Millard, C.; Abdullah, J.; Collart, F.R.; Kim, Y., Donnelly, M.I.  New vectors for co-expression of proteins: Structure of Bacillus subtilis ScoAB obtained by high throughput protocols.  Protein Expr Purif. 53(2):396-403, 2007.
  13. Gerdts CJ, Tereshko V, Yadav MK, Dementieva I, Collart F, Joachimiak A, Stevens RC, Kuhn P, Kossiakoff A, Ismagilov RF.   Time-Controlled Microfluidic Seeding in nL-Volume Droplets to Separate Nucleation and Growth Stages of Protein Crystallization. Angew Chem Int Ed Engl. 45(48):8156-60, 2006.
  14. Osipiuk J, Maltseva N, Dementieva I, Clancy S, Collart F, and Joachimiak A.  Structure of YidB protein from Shigella flexneri shows a new fold with homeodomain motif. Proteins. Proteins. 65(2):509-13, 2006.
  15. Rajan, S.S, Yang, X., Shuvalova, L., Collart, F., Anderson, W.F.  Crystal structure of YfiR, an unusual TetR/CamR-type putative transcriptional regulator from Bacillus subtilis.  Proteins. 65(1):255-7, 2006.
  16. Dieckman, L.J., Zhang, W., Rodi, D.J., Donnelly, M.I., and Collart, F.R.  Bacterial Expression Strategies for Human Angiogenesis Proteins.  J Struct Funct Genomics. 7(1):23-30, 2006.
  17. Borowicz, S., Fackenthal, J., Collart, F.R.; Myatt, E., Moy, S., Babnigg, G., Wilton, R., Boernke, W.E., Schiffer, M., Stevens, F.J., Olopade, O.I. Primary structure-based function characterization of BRCT domain replicates in BRCA1.  Biochem Biophys Res Commun. 345(1):188-96, 2006.
  18. Zhang, R., Joachimiak, G., Jiang, S., Cipriani, A., Collart, F., and Joachimiak, A.  Structure of Phage Protein BC1872 from Bacillus cereus, a singleton with new fold.  Proteins 64(1):280-3, 2006.
  19. Kim, Y., Maltseva, N., Dementieva, I., Collart, F., Holzle, D., Joachimiak A.  Crystal structure of hypothetical protein YfiH from Shigella flexneri at 2 A resolution.  Proteins 1;63(4):1097-101, 2006.
  20. Donnelly, M.I., Zhou, M., Sanville Millard, C., Clancy, S., Stols, L., Eschenfeldt, W.H., Collart, F., Joachimiak, A.  An expression vector tailored for large-scale high throughput purification of recombinant proteins. Protein Expr Purif. 47(2):446-54, 2006.
  21. Lin, C-T., Moore, P.A., Auberry, D.L., Landorf, E.V, Peppler, T., Victry, K.D., Collart, F.R., and Kery, V.  Automated Purification of Recombinant Proteins: Combining High-Throughput with High Yield. Protein Expr Purif.  47 (1) 16-24, 2006.
  22. Dieckman, L.J., Hanly, W.C., and Collart, F.R.  Strategies for High Throughput Gene Cloning and Expression.  Genetic Engineering: Principles and Methods. Vol. 42 (5) 590-596, 2006.
  23. Qiu Y, Tereshko V, Kim Y, Zhang R, Collart F, Yousef M, Kossiakoff A, Joachimiak A.  The crystal structure of Aq_328 from the hyperthermophilic bacteria Aquifex aeolicus shows an ancestral histone fold. Proteins. 62(1):8-16, 2006.
  24. Zhang, R., Minh, T., Lezondra, L., Korolev, S., Moy, S.F., Collart, F., and Joachimiak, A. 1.6 Å Crystal Structure of YteR Protein from Bacillus subtilis, a Predicted Lyase. Proteins: Structure Function and Genetics. 60(3):561-5, 2005.
  25. Nocek B, Chang C, Li H, Lezondra L, Holzle D, Collart F, Joachimiak A. Crystal Structures of Delta(1)-Pyrroline-5-carboxylate Reductase from Human Pathogens Neisseria meningitides and Streptococcus pyogenes.  J Mol Biol. 354(1):91-106, 2005.
  26. Bond DR, Mester T, Nesbo CL, Izquierdo-Lopez AV, Collart FR, Lovley DR. Characterization of citrate synthase from Geobacter sulfurreducens and evidence for a family of citrate synthases similar to those of eukaryotes throughout the Geobacteraceae.  Appl Environ Microbiol. 71(7):3858-65, 2005.
  27. Zhang, R., Minh, T., Lezondra, L., Korolev, S., Moy, S.F., Collart, F., A. Joachimiak.  1.6 Å Crystal Structure of YteR Protein from Bacillus subtilis, a Predicted Lyase. Proteins: Structure Function and Genetics. 60(3):561-5, 2005.
  28. Stevens, F.J., Kuemmel, C., Babnigg, G., and Collart, F.R.  Efficient Recognition of Protein Fold in the Twilight and Midnight Zones by Conservative Application of Psi-BLAST.   J Mol Recognit. 18:150-157, 2005.
  29. Kolker E, Picone AF, Galperin MY, Romine MF, Higdon R, Makarova KS, Kolker N, Anderson GA, Qiu X, Auberry KJ, Babnigg G, Beliaev AS, Edlefsen P, Elias DA, Gorby YA, Holzman T, Klappenbach JA, Konstantinidis KT, Land ML, Lipton MS, McCue LA, Monroe M, Pasa-Tolic L, Pinchuk G, Purvine S, Serres MH, Tsapin S, Zakrajsek BA, Zhu W, Zhou J, Larimer FW, Lawrence CE, Riley M, Collart FR, Yates JR 3rd, Smith RD, Giometti CS, Nealson KH, Fredrickson JK, Tiedje JM.  Global profiling of Shewanella oneidensis MR-1: Expression of hypothetical genes and improved functional annotations.  Proc. Natl. Acad. Sci. U S A. 102:2099-2104, 2005.
  30. Brunzelle J.S., Wu, R., Korolev, S., Collart, F., Joachimiak, A. and Anderson W.F.  Crystal structure of Bacillus subtilis ydaF protein: a putative ribosomal N-acetylransferase.  Proteins: Structure Function and Genetics. 57(4):850-853, 2004.
  31. Rajan SS, Yang X, Shuvalova L, Collart F, Anderson WF.  YfiT from Bacillus subtilis is a probable metal-dependent hydrolase with an unusual four-helix bundle topology.  Biochemistry. 43(49):15472-9, 2004.
  32. Whitehead, J.P., Simpson, F, Hill, M.H., Thomas, E.C., Connolly, L.M., Collart, F., Simpson, R.J. and James, D.E.  Insulin and Oleate Promote Translocation of Inosine-5’Monophosphate Dehydrogenase (IMPDH) to Lipid Bodies.  Traffic. 5(10):739-49, 2004.
  33. Sanishvili, R., Wu, R., Kim, D.E., Watson, J.D., Collart, F., and Joachimiak, A.  Crystal Structure of Bacillus subtilis YckF: Structural and Functional Evolution.  J Struct Biol. 148(1):98-109, 2004.
  34. Rajan SS, Yang X, Collart F, Yip VL, Withers SG, Varrot A, Thompson J, Davies GJ, Anderson WF.  Novel Catalytic Mechanism of Glycoside Hydrolysis Based on the Structure of an NAD(+)/Mn(2+)-Dependant Phospho-alpha-Glucosidase from Bacillus subtilis.  Structure (Camb). 12(9):1619-29, 2004.
  35. Moy, S., Dieckman, L., Schiffer, M., Maltzev, N., Yu, G.X., and Collart, F.R.  Genome-scale expression of proteins from Bacillus subtilis.  J Struct Funct Genomics.  5(1-2):103-9, 2004.
  36. Scholle, M.D., Collart, F.R. and Kay, B.K.  In vivo Biotinylated Proteins as Targets for Phage Display Selection Experiments.  Protein Expr Purif. 37(1):243-52, 2004.
  37. Taneja B, Maar S, Shuvalova L, Collart F, Anderson W, Mondragon.  Structure of the bacillus subtilis YYCN protein: a putative N-acetyltransferase.  Proteins. 53, 950-952, 2003.
  38. Yoon, J., Laible, P. D., Gu, M., Scott, H.N., and F. R. Collart.  Express Primer Tool for High-Throughput Gene Cloning and Expression.  BioTechniques 33, 1328-33, 2002.
  39. Zhang, R.-G.;Vinokour, E.;Grembecka, J.;Collart, F., Dementieva, I.;Minor, W.;Joachimiak, A.  Structure of Bacillus subtilis YXKO - a member of UPF0031 family - a putative kinase. J. Structural Biology 139, 161-70, 2002.
  40. S. Korolev, S., Koroleva, O., Petterson, K., Gu, M., Collart, F., Dementieva, I and Joachimiak, A.   Autotracing of E. coli acetate CoA transferase α-subunit structure using 3.4 Å MAD and 1.9 Å native data.  Acta Crystal D58, 2116-2121, 2002.
  41. Zhang, R-g., Dementieva, I., Duke, N., Collart, F.R.., Quaite-Randall, E., Alkire, L., Dieckman, L., Maltsev, N., Korolev, O., and Jochimiak, J.  Crystal structure of Bacillus subtilus IolI shows Endonuclease IV fold with altered Zn-binding.  Proteins 48, 423-426, 2002.
  42. Dieckman, L., Gu, M., Stols, L., Donnelley, M.I. and Collart, F.R. High throughput methods for gene cloning and expression.  Protein Expression and Purification 25, 1-7, 2002.
  43. Stols, L., Gu, M, Dieckman, L., Raffen, R. Collart, F.R. and Donnelley, M.I.  A new vector for high throughput, ligation independent cloning encoding a TEV protease cleavage site.  Protein Expression and Purification 25 8-15, 2002.
  44. Zhang R, Evans G, Rotella F, Westbrook E, Huberman E, Joachimiak A, Collart FR.  Discriminatory signature of bacterial and mammalian IMPDH enzymes.  Current Med Chem.  6, 537-43, 1999.
  45. Laouar, A., Chubb, C.B.H., Collart, F.R., and Huberman, E.  Human macrophage differentiation requires an interaction between integrins and fibronectin.  J. Immunol. 162, 407-414, 1999.
  46. Zhang, R., Evans, G., Rotella, F.J., Westbrook, E.M., Beno, D., Huberman, E., Joachimiak, A., and Collart, F.R. Characteristics and crystal structure of bacterial inosine 5-monophosphate dehydrogenase.  Biochemistry 38, 4691-4700, 1998.
  47. Franchetti, P., Cappellacci, L., Jayaram, H.N., Butler, A., Schneider, B.P., Collart, F.R., Huberman, E., Grifantini, M.  Isosteric analogues of nicotinamide adenine dinucleotide derived from furanfurin, thiophenfurin, and selenophenfurin as mammalian inosine monophosphate dehydrogenase (type I and type II) inhibitors.  J. Med. Chem. 41, 1702-1707, 1998.
  48. Franchetti, P.,  Cappellacci, L., AbuSeikha, G., Jayaram, H.N., Schneider, B.P., Sint, T.,  Gurudutt, V.V., Collart, F.R., Huberman, E., Grifantini, M.  Synthesis and IMP dehydrogenase (type I and type II) inhibitory activity of isosteric NAD analogs derived from thiophenfurin and furanfurin. Nucleosides and Nucleoides 16, 1415-1418, 1997.
  49. Collart, F.R., Osipiuk, J., Trent, J., Olsen, G.J. and Huberman, E.  Cloning and characterization of the gene encoding IMP dehydrogenase from Arabidopsus thaliana.  Gene, 174, 217-220, 1996.
  50. Collart, F.R., Osipiuk, J., Trent, J., Olsen, G.J. and Huberman, E.  Cloning, characterization, and sequence comparison of the gene coding for IMP dehydrogenase from Pyrococcus furiosus.  Gene, 174, 206-216, 1996.
  51. Salzberg, S., Heller, A., Zou, J-P., Collart, F.R., Huberman, E. Interferon-independent activation of (2'-5')oligoadenylate synthetase in Friend erythroleukemia cell variants exposed to HMBA.  J. Cell Science, 109, 1517-1526, 1996.
  52. Hager, P.W., Collart, F.R., Huberman, E., and Mitchell, B.S. Recombinant human inosine monophosphate dehydrogenase type I and type II proteins: Purification and characterization of inhibitor binding.  Biochem. Pharmacol., 49, 1323-1329, 1995.
  53. Collart, F.R., Horio, M., and Huberman, E.  Heterogeneity in c-jun gene expression in normal and malignant cells exposed either to ionizing radiation or hydrogen peroxide.  Radiation Res., 142, 188-196, 1995.
  54. Jiang, H., Lin, J., Su, Z., Collart, F.R., Huberman, E., and Fisher, P.B.  Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53. Oncogene 9, 3397-3406, 1994.
  55. Huberman E, Glesne D, Collart F.  Regulation and role of inosine-5'-monophosphate dehydrogenase in cell replication, malignant transformation, and differentiation.  Adv Exp Med Biol. ;370:741-6, 1994.
  56. Gharehbaghi, K., Burgess, G.S., Collart, F.R., Litz-Jackson, S., Huberman, E., Jayaram, H.N.  p210 Bcr-Abl confers overexpression of inosine monophosphate dehydrogenase: an intrinsic pathway to drug resistance mediated by an oncogene.  Leukemia 8, 1259-1263, 1994.
  57. Warner-Bartnicki, A.L., Murao, S., Collart, F.R. and Huberman, E.  Regulated expression of the MRP8 and MRP14 genes in human promyelocytic leukemic HL-60 cells treated with the differentiation-inducing agents mycophenolic acid and 1α, 25-dihydroxyvitamin D3. Experimental Cell Res. 204, 241-246, 1993.
  58. Glesne, D., Collart, F., Varkony, T., Drabkin, H., and Huberman, E.  Chromosomal localization and structure of the human Type II IMP dehydrogenase gene.  Genomics 16, 274-277, 1993.
  59. Tonetti, D.A., Horio, M., Collart, F.R., and Huberman, E.  Protein kinase C b gene expression is associated with susceptibility of human promyelocytic leukemia cells to phorbol ester-induced differentiation.  Cell Growth Differen. 3, 739-745, 1992.
  60. Collart, F.R., Horio, M., Schlenker, R., Kathren, R.L., and Huberman, E. Alteration of the c-fms gene in a blood sample from a Thorotrast individual.  Health Physics 63, 27-32, 1992.
  61. Collart, F.R., Chubb, C.B., Mirkin, B.L., Huberman, E.  Increased inosine-5'-phosphate dehydrogenase gene expression in solid tumor tissues and tumor cell lines.  Cancer Res. 52, 5826-5828, 1992.
  62. Glesne, D., Collart, F.R., and Huberman, E.  Human IMP dehydrogenase expression regulated by end products, guanine nucleotides.  Mol. Cell. Biol. 11, 5417-5425, 1991.
  63. Wilson, K., Collart, F.R., Huberman, E., Stringer, J.R., and Ullman, B.  Amplification and molecular cloning of the IMP dehydrogenase gene of Leishmania donovani.  J. Biol. Chem. 266, 1665-1671, 1991.
  64. Murao, S., Collart, F.R., and Huberman, E.  A protein complex expressed during terminal differentiation of monomyelocytic cells is an inhibitor of cell growth.  Cell Growth Differen. 1, 447-454, 1990.
  65. Kiguchi, K., Collart, F.R., Henning-Chubb, C., and Huberman, E.  Induction of cell differentiation in melanoma cells by inhibitors of IMP dehydrogenase: Altered patterns of IMP dehydrogenase expression and activity.  Cell Growth and Differen. 1, 259-270, 1990.
  66. Kiguchi, K., Collart, F.R., Henning-Chubb, C., and Huberman, E.  Cell differentiation and altered IMP dehydrogenase expression induced in T-lymphoblastoid leukemia cells.  Experimental Cell Res.  187, 47-53, 1990.
  67. Collart, F.R. and Huberman, E.  Expression of IMP dehydrogenase in differentiating HL-60 cells.  Blood 75, 570-576, 1990.
  68. Murao, S., Collart, F.R., and Huberman, E.  A protein containing the cystic fibrosis antigen is an inhibitor of specific protein kinases.  J. Biol. Chem.  264, 8356-8360, 1989.
  69. Collart, F.R. and Huberman, E.  Cloning and sequence analysis of the human and Chinese hamster inosine-5'-monophosphate dehydrogenase cDNAs.  J. Biol. Chem.  263, 15769-15722, 1989.
  70. Collart, F.R. and Huberman, E.  Amplification of the IMP dehydrogenase gene in Chinese hamster cells resistant to mycophenolic acid.  Mol. Cell. Biol.  7, 3328-3331, 1987.
  71. Scovell, W.M. and Collart, F.R.  The Unwinding angle for cis- and trans-(NH3)2PtCl2 on supercoiled ΦX174 RF DNA.  Nucleic Acid Res.  13, 2881-2895, 1985.

 

Book Chapters/Technical Reports

  1. Giuliani, S. E., Landorf, E. V., and Collart, F. R.  Protein production for biotechnology.  In: Encyclopedia of Life Sciences.  Wiley Press, 2007
  2. Collart, F.R. and Huberman, E.  Identification of Specific Inhibitors of IMP Dehydrogenase.  In: “Inosine Monophosphate Dehydrogenase; A Major Therapeutic Target,”  K. W. Pankiewicz and B.M. Goldstein, Eds. ACS Symposium Series Vol. 839, 283-293, 2002.
  3. Collart, F.R.  Automated Cloning Methods.  ANL Technical Report, ANL-BIO01. September 2001.
  4. Laouar, A., Collart, F.R., and Huberman, E.  Induction of differentiation in human myeloid HL-60 leukemia cells.  In: "Cell Biology: A Laboratory Handbook"  J.E. Celis, Ed.  Academic Press, San Diego, CA, pp. 233-238, 1997.
  5. Collart, F.R., Tonetti, D.A. and Huberman, E.  The control of multiplication and differentiation in human myelomonocytic leukemia cells.  In: "Regulation of Cell Growth, Differentiation and Genetics in Cancer", N. D'Alessanddro, E. Mihich, L. Rausa, H. Tapiero, T. R. Tritton, eds., NATO ASI Series, Springer-Verlag, Berlin, Vol H99, 113-128, 1996.
  6. Huberman, E., Glesne, D., and Collart, F.R. Regulation and Role of Inosine 5'-monophosphate dehydrogenase in cell replication, malignant transformation, and differentiation.  In: "Purine and Pyrimidine Metabolism in Man, VIII", A. Sahota and M. Taylor, Eds. Plenum Press, New York, 1995, pp. 741-746.
  7. Huberman, E., Tonetti, D.A., Horio, M., Murao, S., and Collart, F.R.  The control of cell multiplication and differentiation in human myelomonocytic cells.  In: "Specific Approaches to Cancer Therapy; Differentiation, Immunomodulation and Angiogenesis", N. D'Alessanddro, E. Mihich, L. Rausa, H. Tapiero, T. R. Tritton, eds., NATO ASI Series, Vol. H75, pp. 17-23 1993.
  8. Collart, F.R. and Huberman, E.  Amplification of the IMP dehydrogenase gene in mammalian cells.  In: "Gene Amplification in Mammalian Cells", R. Kellems, Ed., Marcel Dekker, Inc., (New York), pp 149-158, 1992.
  9. Murao, S., Collart, F.R., and Huberman, E.  A protein complex expressed during terminal differentiation of monomyelocytic cells is an inhibitor of growth.  In: "The Status of Differentiation Therapy of Cancer", Vol. II, Waxman & Rossi, Eds., Raven Press, (New York, Rome) 1991.
  10. Huberman, E. and Collart F.R.  Somatic mutation and cell differentiation in neoplastic transformation.  Proceedings of the 8th International Congress of Radiation Research, Edinburgh, 519-525, July, 1987.

 

PATENTS

  1. US Patent 5,665,583: issue date September 9, 1997.  Methods and Materials Relating to IMPDH and GMP Production.  .  F.R Collart and E. Huberman.
  2. US Patent 6,147,194: issue date November 14, 2000.  Eukaryotic IMPDH polynucleotide and antibody compositions.  F.R Collart and E. Huberman.
  3. US Patent 6,153,398: issue date November 28, 2000.  Method to identify specific inhibitors of IMP dehydrogenase.  F.R Collart and E. Huberman.
  4. US Patent 6,479,628: issue date November 12, 2002.  Methods and Materials Relating to IMPDH and GMP Production (Continuation).  Inventors, F.R. Collart and E. Huberman.  Inventors: F.R. Collart, E. Huberman.
  5. US Patent 6,826,488, issue date November 30, 2004, Crystals, molecular complexes, and methods of developing lead compounds for inhibitors of bacterial IMPDH.  Inventors: F.R. Collart, E. Huberman, A. Joachimiak, E.M. Westbrook, and R. Zhang

 

INVENTION REPORTS:

ANL-IN-86-72 Plant or Animal Organism with Increased Amounts of GMP.
F.R. Collart and E. Huberman
ANL-IN-88-18 Synthetic DNA Construct, Cells, and Artificial Animals
F.R. Collart and E. Huberman
ANL-IN-90-66 Method for Detecting Tumor Cells.
F.R. Collart and E. Huberman
ANL-IN-94-032 New Material Relating to IMPDH and GMP Production.
F.R. Collart, E. Huberman, J. Osipiuk, and J. D. Trent
ANL-IN-94-068 DNA sequence from Arabisopsis thaliana.
F.R. Collart, E. Huberman, J. Osipiuk, and J. D. Trent
ANL-IN-97-053 A Method to Identify Specific Inhibitors of IMP Dehydrogenases.
F.R. Collart and E. Huberman
ANL-IN-98-058 A Method to Design Drugs for the Inhibition of Microbial Growth.
F.R. Collart, E. Huberman, A. Joachimiak, E.M. Westbrook, and R. Zhang
ANL-IN-00-014 Universal Genomic Detector: A Generic Method for Identification and Comparison of Genomic Material.
F. Stevens and F.R Collart.
ANL-IN-00-02 Inhibitors of microbial IMPDH enzymes
F.R. Collart, E. Huberman, A.  Joachimiak, E.M. Westbrook, and R. Zhang
ANL-IN-00-083 Method to optimize recombinant protein expression
F.R. Collart, M. Donnelly, and L. Stols.
ANL-SF-03-22 Express Primer Tool for High-throughput Gene Cloning and Expression
F.R. Collart, Gu, M., Laible, P. D., Scott, H.N, Stevens, F.J., and Yoon, J.
 
U.S. Department of Energy Office of Science | UChicago Argonne LLC
Privacy & Security Notice | Contact Us | Site Map | Search