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Structural Biology

The Midwest Center for Structural Genomics
The Midwest Center for Structural Genomics (MCSG) is a consortium of the Argonne National Laboratory, European Bioinformatics Institute, Northwestern University, University of Toronto, Washington University, University College London, University of Virginia and the ... Read more  
 
Center for Structural Genomics of Infectious Diseases
CSGID applies state-of-the-art high-throughput (HTP) structural biology technologies to experimentally characterize the three dimensional atomic structure of targeted proteins from pathogens in the NIAID Category A-C priority lists and organisms causing emerging and re-emerging infectious diseases ... Read more
Researchers from the Biosciences division are collaborating on this project.
   
Structural Correlates of Protein Function
We focus on the characterization and structure determination of proteins.  Our ultimate goal is to understand how the structures and functions of proteins are related.  The samples that we work with include proteins that are important in (1) bioremediation (multiheme cytochromes, heme based sensors), (2) biofuels (hydrolytic enzymes), (3) human health (immunoglobulin light chains), and (4) photosynthesis (reaction center) ...Read more
   
Membrane Protein Engineering
Membrane-bound proteins pose particular challenges for biochemical and biophysical studies.  Our development of novel expression systems and stabilizing reagents for membrane proteins advances the potential for study of these highly specialized molecular systems.Read more
   
Protein Stability Engineering
Proteins such as antibodies and enzymes represent a rich source of molecular recognition tools and catalytic reagents that is unmatched in other materials. Protein reagents have wide ranging applications from field-deployable biosensors and industrial processes to human therapeutics.Read more

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